Objective:
To investigate serum paraoxonase (PON1) activity, serum calcium, and lipid profiles in pre-eclampsia.
Material & Method:
Serum PON1 activity, calcium, and lipid profiles were measured in a cohort of 45 women with normal pregnancies (11 patients) and pre-eclampsia (34 patients).
Results:
Triglyceride, total cholesterol, and LDL cholesterol concentrations were significantly increased in women with pre-eclampsia, compared with women with normal
Pregnancies:
Serum HDL cholesterol, PON1, and calcium levels in pre-eclamptic patients were significantly lower than those in healthy pregnant women.
Conclusion:
The significant decrease of PON1 activity in pre-eclampsia is related to lipid profiles and calcium.
Keywords: Pre-eclampsia, serum paraoxonase (PON1), lipid profile, calcium