Clinical Investigation

Diagnostic value and timing of serum antichlamidial antibody level evaluation during infertility workup among infertile women in whom tubal factor was detected with diagnostic laparoscopy


  • Serkan Kahyaoğlu
  • İnci Kahyaoğlu
  • Necdet Süt
  • Mehmet Aydın
  • Leyla Mollamahmutoğlu
  • Utku Özcan

Turk J Obstet Gynecol 2012;9(1):47-54


With normal hysterosalpingography (HSG) results, selecting suitable candidates for the laparoscopic treatment of probable pelvic adhesions following previous pelvic inflammatory disease, it would be wise to investigate serum antibody screening against chlamidia trachomatis. It is worth to evaluate whether it is useful to detect a negative antichlamidial antibody disease for cancelling laparoscopy for a while with abnormal HSG findings. These two subjects have been investigated in study.


For detecting diagnostic value of serum antichlamidial antibody, in our infertility clinic, postoperative blood samples of 80 patients who were hospitalized for diagnostic laparoscopy to investigate infertility ethiology between May 2004 and November 2005 have been tested with microelisa method for antichlamidial IgM and IgG antibodies. HSG films of the patients performed at least one year were evaluated. Venous blood was drawn from these patients during postoperative early period for studying serum IgM and IgG antibodies of chlamidia trachomatis and the results were compared with operative findings.


According to the antichlamidial antibody levels 60 (75%) patients have not been infected with chlamidia and 20 (25%) patients have been infected previously. When the patients were divided to two groups; normal and abnormal; based on preoperative HSG films; 18 (30%) of the 60 patients with abnormal HSG films and 2 (10%) of the 20 patients with normal HSG films had positive antichlamidial antibody levels respectively.


The relationship between chlamidia trachomatis infection and tubal infertility has been demonstrated among 85% of patients with positive antichlamidial antibody levels and 46.7% of patients with negative levels who had tubal passage defects detected during diagnostic laparoscopy.

Keywords: tubal factor, infertility, diagnostic laparoscopy, antichlamidial antibody