ABSTRACT

To investigate the effects of endometrial thickness measurements and serum hormone levels on the outcomes of long protocol GnRH agonist ICSI cycles.

Forty consecutive infertile women undergoing controlled ovarian hyperstimulation with recombinant FSH and GnRH agonists for ICSI were enrolled in this study. Age of the patients, day 3 FSH, antral follicle count (AFS), serum E2 levels on day 3, E2 on stimulation day 5, E2 on day of hCG administration, endometrial thickness on the baseline (EKbazal), on day 5 of stimulation (EK5), on day of hCG administration (EKhCG) and cycle outcomes were recorded. The outcomes of pregnant and non-pregnant women were compared.

Women’s age was 27,4 ± 4,8. Overall pregnancy rate was %45 (n = 18) and spontaneous abortion rate was %11,1 (n = 2). In pregnant women, EK5, EKhCG, ∆EKhCG-Bazal values were significantly higher than non-pregnant women. There were no significant differences in estradiol and progesteron levels between pregnant and non-pregnant women.

For achieving pregnancy, endometrial thickness may be a determining factor in GnRH agonist down-regulated ICSI cycles.